6.95994 % | Commodore Capital LP | 4,747,373 | 319,301 | 31.12.2023 |
5.87090 % | Incyte Corp | 4,004,544 | 0 | 25.3.2024 |
5.00280 % | Samlyn Capital, LLC | 3,412,410 | 155,892 | 31.12.2023 |
4.42736 % | Deerfield Management Company, L.P. | 3,019,901 | -857,037 | 31.12.2023 |
4.03521 % | BVF Partners L.P. | 2,752,420 | 0 | 31.12.2023 |
3.47988 % | RTW Investments L.P. | 2,373,625 | 376,861 | 31.12.2023 |
3.36857 % | Federated Hermes Global Investment Management Corp. | 2,297,700 | -1,339,609 | 29.2.2024 |
3.14941 % | VR Adviser, LLC | 2,148,214 | 422,000 | 31.12.2023 |
2.94591 % | Wellington Management Company, LLP | 2,009,403 | -725,844 | 31.12.2023 |
2.78552 % | Boxer Capital, L.L.C. | 1,900,000 | 0 | 31.12.2023 |
2.74944 % | Franklin Advisers, Inc. | 1,875,391 | -9,135 | 31.12.2023 |
1.92202 % | Driehaus Capital Management, LLC | 1,311,013 | 175,818 | 31.12.2023 |
1.80800 % | Balyasny Asset Management LP | 1,233,238 | 372,879 | 31.12.2023 |
1.80737 % | Pictet Asset Management Ltd. | 1,232,808 | 268,961 | 31.12.2023 |
1.71387 % | Medicxi Ventures (UK) LLP | 1,169,028 | -430,972 | 31.3.2024 |
1.66431 % | Lynx1 Capital Advisors LLC | 1,135,225 | -15,000 | 31.12.2023 |
1.30316 % | Avoro Capital Advisors LLC | 888,888 | 444,444 | 31.12.2023 |
1.27851 % | Rock Springs Capital Management LP | 872,069 | 33,641 | 31.12.2023 |
1.15817 % | BlackRock Financial Management, Inc. | 789,986 | 242 | 31.12.2023 |
1.09449 % | Two Sigma Investments, LP | 746,553 | 469,263 | 31.12.2023 |
1.09438 % | Frazier Healthcare Partners | 746,479 | 0 | 31.12.2023 |
1.07089 % | Fidelity Management & Research Company LLC | 730,453 | -44,500 | 31.12.2023 |
1.05154 % | Fairmount Funds Management LLC | 717,254 | -1,164,091 | 31.12.2023 |
1.01646 % | Millennium Management LLC | 693,327 | 64,128 | 31.12.2023 |
0.94646 % | SilverArc Capital Management, LLC | 645,581 | 145,581 | 31.12.2023 |
0.77854 % | Janus Henderson Investors | 531,044 | 332,756 | 31.12.2023 |
0.76460 % | 5AM Ventures | 521,531 | 521,531 | 31.12.2023 |
0.73568 % | StemPoint Capital LP | 501,806 | 501,806 | 31.12.2023 |
0.70404 % | Candriam Luxembourg S.A. | 480,227 | 0 | 29.2.2024 |
0.66687 % | Dafna Capital Management, LLC | 454,870 | -30,000 | 31.12.2023 |
0.59208 % | Carmignac Gestion | 403,861 | -50,470 | 31.12.2023 |
0.57079 % | Saturn V Capital Management LLC | 389,333 | 349,267 | 31.12.2023 |
0.56987 % | BlackRock Institutional Trust Company, N.A. | 388,708 | -33,448 | 31.12.2023 |
0.55487 % | Goldman Sachs & Company, Inc. | 378,477 | 172,500 | 31.12.2023 |
0.54344 % | Braidwell LP | 370,679 | -1,530,658 | 31.12.2023 |
0.52061 % | Aquilo Capital Management, LLC | 355,109 | -75,000 | 31.12.2023 |
0.48598 % | Medical Strategy GmbH | 331,487 | 0 | 31.12.2023 |
0.48380 % | Adage Capital Management, L.P. | 330,000 | 230,000 | 31.12.2023 |
0.44360 % | Soleus Capital Management, L.P. | 302,577 | -81,913 | 31.12.2023 |
0.44353 % | Morgan Stanley & Co. LLC | 302,531 | 113,386 | 31.12.2023 |
0.41086 % | Citadel Advisors LLC | 280,251 | 277,066 | 31.12.2023 |
0.40305 % | Ally Bridge Group NY LLC | 274,923 | 53,539 | 31.12.2023 |
0.37739 % | Candriam Belgium S.A. | 257,419 | -605,657 | 30.11.2023 |
0.35659 % | Woodline Partners LP | 243,229 | 0 | 31.12.2023 |
0.34553 % | State Street Global Advisors (US) | 235,688 | 15,910 | 31.12.2023 |
0.33768 % | Sphera Funds Management Ltd. | 230,333 | -23,000 | 31.12.2023 |
0.30452 % | BlackRock Advisors (UK) Limited | 207,715 | -129 | 31.3.2024 |
0.27441 % | BlackRock Asset Management Ireland Limited | 187,172 | 2,031 | 31.12.2023 |
0.27313 % | T. Rowe Price Investment Management, Inc. | 186,300 | 186,300 | 31.3.2024 |
0.24791 % | AllianceBernstein L.P. | 169,098 | -23,186 | 31.12.2023 |
0.23137 % | Parkman Healthcare Partners LLC | 157,817 | 27,082 | 31.12.2023 |
0.22873 % | Liu (Hui) | 156,016 | 98,085 | 15.3.2024 |
0.22295 % | Lundberg (Sven Ante) | 152,071 | 0 | 15.3.2024 |
0.20940 % | The Vanguard Group, Inc. | 142,833 | -27,093 | 31.12.2023 |
0.20822 % | Platinum Asset Management | 142,029 | 0 | 31.12.2023 |
0.20091 % | Nan Fung Life Sciences | 137,038 | 0 | 31.12.2023 |
0.19582 % | HighVista Strategies LLC | 133,572 | 10,941 | 31.12.2023 |
0.18546 % | Cubist Systematic Strategies, LLC | 126,505 | 126,505 | 31.12.2023 |
0.17783 % | UBS O'Connor LLC | 121,300 | -30,806 | 31.12.2023 |
0.16966 % | Eversept Partners, LP | 115,726 | -18,284 | 31.12.2023 |
0.16127 % | DWS Investment GmbH | 110,000 | 0 | 31.12.2023 |
0.14651 % | Morgan Stanley Investment Management Inc. (US) | 99,934 | -51,326 | 31.12.2023 |
0.13777 % | Allianz Global Investors U.S. LLC_NLE | 93,975 | 0 | 30.9.2023 |
0.13777 % | Voya Investment Management LLC | 93,975 | 0 | 31.12.2023 |
0.13091 % | Wellington Management Japan Pte Ltd | 89,295 | -61,818 | 30.6.2023 |
0.12784 % | Hudson Bay Capital Management LP | 87,200 | -80,618 | 31.12.2023 |
0.12755 % | Nomura Asset Management Co., Ltd. | 87,000 | 87,000 | 30.11.2023 |
0.10787 % | Iwicki (Mark T.) | 73,576 | 73,576 | 15.3.2024 |
0.10652 % | Schweizerische Nationalbank | 72,654 | -20,700 | 31.12.2023 |
0.10106 % | Algert Global LLC | 68,933 | -1,549 | 31.12.2023 |
0.09211 % | BNP Paribas Securities Corp. North America | 62,825 | 36,160 | 31.12.2023 |
0.08840 % | Norges Bank Investment Management (NBIM) | 60,300 | -14,700 | 31.12.2023 |
0.08655 % | D. E. Shaw & Co., L.P. | 59,033 | 59,033 | 31.12.2023 |
0.08210 % | Deka Vermögensmanagement GmbH | 56,000 | 31,000 | 31.12.2023 |
0.08210 % | HBM Partners AG | 56,000 | 5,000 | 30.9.2023 |
0.07859 % | Geode Capital Management, L.L.C. | 53,608 | 150 | 31.12.2023 |
0.07038 % | Campbell & Company, Inc. | 48,007 | 48,007 | 31.12.2023 |
0.07026 % | MFS Investment Management | 47,926 | -1,447 | 29.2.2024 |
0.06774 % | Invesco Capital Management LLC | 46,208 | 46,208 | 31.12.2023 |
0.06761 % | Jump Financial, LLC | 46,120 | 46,120 | 31.12.2023 |
0.06596 % | Credit Suisse Funds AG | 44,990 | -3,675 | 31.12.2023 |
0.06403 % | Nuveen LLC | 43,677 | -14,214 | 31.12.2023 |
0.05936 % | Trexquant Investment LP | 40,489 | 23,503 | 31.12.2023 |
0.05883 % | Alps Advisors, Inc. | 40,128 | 40,128 | 31.12.2023 |
0.05730 % | ExodusPoint Capital Management, LP | 39,087 | 39,087 | 31.12.2023 |
0.05727 % | T. Rowe Price Associates, Inc. | 39,064 | 9,569 | 29.2.2024 |
0.05627 % | Assenagon Asset Management S.A. | 38,383 | 2,820 | 29.2.2024 |
0.05574 % | Northern Trust Investments, Inc. | 38,022 | 952 | 31.12.2023 |
0.05538 % | HRT Financial LP | 37,773 | 11,265 | 31.12.2023 |
0.05512 % | Schonfeld Strategic Advisors LLC | 37,600 | -201,770 | 31.12.2023 |
0.05487 % | UBS Asset Management (Americas), Inc. | 37,426 | -1,093 | 31.3.2023 |
0.05211 % | Atom Investors LP | 35,544 | 21,976 | 31.12.2023 |
0.05158 % | First Trust Advisors L.P. | 35,185 | 1,247 | 31.12.2023 |
0.05076 % | Legal & General Investment Management Ltd. | 34,621 | -1,848 | 31.12.2023 |
0.04810 % | California State Teachers Retirement System | 32,809 | -4,759 | 31.12.2023 |
0.03756 % | State of Wisconsin Investment Board | 25,618 | -1,737 | 31.12.2023 |
0.03665 % | Deka Investment GmbH | 25,000 | 20,600 | 31.12.2022 |
0.03646 % | Sanders Morris LLC | 24,870 | 0 | 31.3.2024 |
0.03611 % | Susquehanna Portfolio Strategies, LLC | 24,628 | 24,628 | 31.12.2023 |
0.03583 % | Tudor Investment Corporation | 24,443 | 805 | 31.12.2023 |